Category Archives: Blog

BSL-3 Sterilization

The Process of Effluent Sterilization

Unique equipment design from Beta Star provides additional layer of safety and sterilization of cycle effluent.

For effective sterilization, especially critical in BSL-3 laboratories and facilities, identifying the piping configuration, load configuration, and cycle parameters which minimize condensate generation are vital components of effective sterilization. This is vitally important, as our studies have shown that pooling condensate in the bottom of the chamber acts as an insulant against complete sterilization for any harmful pathogens that have made their way to the chamber drain. In BSL-3 situations, pathogens that have been insulated from complete sterilization present a serious hazard to the safety of our end users, service personnel, and the environment as the infected condensate is allowed down the drain.

While effective piping and load configurations minimize condensate generation during cycle, all steam sterilizers (autoclaves) generate condensate during operation. Beta Star sterilizers monitor and control sterilizer temperature set-point at the chamber exhaust port. The period of time between the exhaust port reaching the sterilization set-point (typically 121°C) and the load achieving that same set-point is known as lag time. Lag time will vary dependent on load type and cycle selection. For all steam sterilizers, condensate generation is greatest during this lag time. When steam contacts the sterilization load, such as carts, bedding, and cages, while the load is at room temperature, it rapidly cools and condenses upon contact with machine and load surfaces.

To study the insulation properties of the pooling condensate, we looked at the temperature differential between the liquid condensate and the sterilization threshold (in this test, that was 121°C). Our tests revealed that this liquid can be as low as 70°C, over 50°C below the industry accepted set point. 

Chamber Drain Injection Effluent Arrangement

To solve this problem, our engineering team was tasked with creating a solution to solve the effluent insulant problem detailed above. This led to the development of the dual steam injection system, one port for the chamber and one port for the chamber drain. With the development of this Chamber Drain Injection Effluent sterilizer arrangement, Beta Star has ensured the greatest possible pathogen lethality by providing direct steam impingement into the condensate pool which all sterilizers product. The direct steam injection port in the chamber drain significantly increases the temperature in the drain effluent.

Connecting With Your Work

We Are Getting Social!

At Beta Star, we are passionate about the quality of the design and manufacturing process of our sterilizers. However, that is only one small part of our customer’s world. To join in the biotechnology, research, and pharmaceutical conversations that our customers care about the most, we are launching the Beta Star LinkedIn page today.

Be sure to visit the page, give us a Follow, and get Beta Star and industry alerts delivered right to you.


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Customized Steam Sterilizer (Autoclave)

Record Setting Sized Sterilizer

Spatial constraints are a necessary consideration with many sterilizer installations. Beta Star has a solution. With our engineering and manufacturing capabilities, we can customize laboratory equipment to meet customer specifications in both new and existing laboratory space.

Currently, Beta Star is in the process of manufacturing a laboratory sterilizer with the largest chamber size we have ever built for a lift and swing sterilizer. Our customer requested increased sterilizer capacity without exceeding their current spatial capacity. As the customer did not want to rebuild, Beta Star engineered the 64” wide x 92” high x 96” long sectional bulk sterilizer. The vessel weighs 14,300 pounds and has an interior volume of 9,263 liters.

Features


This steam sterilizer has the deepest chamber that could fit into the facility space and uses a higher and wider than average split chamber to accommodate large containers in bulk.

Beta Star’s sectional bulk design permits egress of several small vessel components through the facility to the installation space. There the vessel will be reassembled and Beta Star’s ASME Code fabricators will perform the final field welds so that the sterilizer can be commissioned.

Beta Star engineered an additional space saving solution by offering an electrically actuated bulk lift and swing door sterilizer. This unique design provides a nearly silent lift of the door through the use of clean, efficient electric actuators.

Furthermore, it provides the largest in class sterilizer volume while reducing the need for expensive facility renovation and reducing the overall installation footprint. Beta Star continually provides innovative solutions to meet unique specifications while keeping equipment cost-efficient.


“The new lift and swing door design was set-up to be a success. The whole Beta Star team came together and shared everything they could to make it a success. … It was an atmosphere that I was proud to be a part of and an atmosphere that would not settle for failure.”

Jim Taylor, Beta Star Engineer

Quality Service


Showcasing Beta Star’s dedication to providing low maintenance and easily serviceable products, the sterilizer’s material selection, bearing surfaces, rotating elements and lifting mechanisms were all optimized for this application. Additionally, all rotating elements are self-lubricating and permit a single operator to manipulate a door weighing more than 3,000 pounds.

Another option offered to increase efficiency is the Beta Connect System. This system offers remote control access allowing for real-time data management and faster troubleshooting and servicing.

If you have a project you would like to discuss, reach out to us or read about our experience in manufacturing steam sterilizers for multiple industries.